Fifftydents unique formula is insoluble in water so it will not wash out when eating or drinking. Directions: 1) Remove dentures and brush them under running water with a toothbrush. 2) Drop half or one tablet into enough warm water to cover denture or orthodontic brace. 3)Place denture or brace into effervescing. 4) Leave denture or brace into effervescing. 5) Remove and rinse denture or brace under running water. 6) Dry denture thoroughly before applying fittydent denture adhesive or cushions on dentures.